Antibiotic prophylaxis

  • Antibiotic prophylaxis

    Posted by Angie Blackwell on June 27, 2018 at 1:03 pm

    ​​I was wondering if any of your facilities routinely prescribe prophylactic antibiotics to AML or ALL patients during periods of prolonged neutropenia in an attempt to reduce blood stream infections? If so what antibiotic regimen do you use, and what effects have you seen on your CLABSI/MBI rate?
    I appreciate any information you have. Thank you!

    ——————————
    Angie Blackwell,
    MSN, RN, CNS, CPON
    Orange County, CA
    United States
    ——————————

    Melissa Beauchemin replied 5 years, 5 months ago 3 Members · 2 Replies
  • 2 Replies
  • Jessica Edgar

    Member
    September 14, 2018 at 2:31 pm

    Hi,

    Yes. About three months ago our institution began prescribing daily levaquin for AML and Relapse ALL patients when ANC < 250 and stopping when put on triples or when ANC > 250 if they never became febrile as part of our way to prevent gram negative bacteremia. We discussed with ID as well as other pediatric institutions who also did the same and gathered and evaluated the data before making the change. 

    ——————————
    Jessica Edgar CPNP
    Inpatient PNP, Oncology
    Phoenix Children’s Hospital
    Phoenix, Arizona
    USA
    ph 623-640-2264
    work 602-933-1000 ext 8712
    jedgar@ phoenixchildrens.org
    ——————————
    ——————————————-
    Original Message:
    Sent: 06-27-2018 01:02 PM
    From: Angie Blackwell
    Subject: Antibiotic prophylaxis

    ​​I was wondering if any of your facilities routinely prescribe prophylactic antibiotics to AML or ALL patients during periods of prolonged neutropenia in an attempt to reduce blood stream infections? If so what antibiotic regimen do you use, and what effects have you seen on your CLABSI/MBI rate?
    I appreciate any information you have. Thank you!

    ——————————
    Angie Blackwell,
    MSN, RN, CNS, CPON
    Orange County, CA
    United States
    ——————————

    • Melissa Beauchemin

      Member
      September 14, 2018 at 8:56 pm

      Hi,

      This provides information on ABX prophylaxis:

      https://jamanetwork.com/journals/jama/article-abstract/2702147

      Melissa Beauchemin, MPhil, RN, CPNP, CPON 

      PhD Student

      Columbia University School of Nursing

       

      Program Administrator CUMC Minority Underserved NCI Community Oncology Research Program

      Columbia University Medical Center

      ——Original Message——

      Hi,

      Yes. About three months ago our institution began prescribing daily levaquin for AML and Relapse ALL patients when ANC < 250 and stopping when put on triples or when ANC > 250 if they never became febrile as part of our way to prevent gram negative bacteremia. We discussed with ID as well as other pediatric institutions who also did the same and gathered and evaluated the data before making the change. 

      ——————————
      Jessica Edgar CPNP
      Inpatient PNP, Oncology
      Phoenix Children’s Hospital
      Phoenix, Arizona
      USA
      ph 623-640-2264
      work 602-933-1000 ext 8712
      jedgar@ phoenixchildrens.org
      ——————————

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