Reply To: Antibiotic prophylaxis

  • Jessica Edgar

    September 14, 2018 at 2:31 pm


    Yes. About three months ago our institution began prescribing daily levaquin for AML and Relapse ALL patients when ANC < 250 and stopping when put on triples or when ANC > 250 if they never became febrile as part of our way to prevent gram negative bacteremia. We discussed with ID as well as other pediatric institutions who also did the same and gathered and evaluated the data before making the change. 

    Jessica Edgar CPNP
    Inpatient PNP, Oncology
    Phoenix Children’s Hospital
    Phoenix, Arizona
    ph 623-640-2264
    work 602-933-1000 ext 8712
    Original Message:
    Sent: 06-27-2018 01:02 PM
    From: Angie Blackwell
    Subject: Antibiotic prophylaxis

    ​​I was wondering if any of your facilities routinely prescribe prophylactic antibiotics to AML or ALL patients during periods of prolonged neutropenia in an attempt to reduce blood stream infections? If so what antibiotic regimen do you use, and what effects have you seen on your CLABSI/MBI rate?
    I appreciate any information you have. Thank you!

    Angie Blackwell,
    Orange County, CA
    United States