Reply To: CAR-T Referral Management

  • Mary Lynn Rae

    October 26, 2017 at 9:08 am

    We have only done one patient and it was an internal patient.  The ONC team managed the chemo and labs prior to the collection and then the SCT team took over from there…..


    Mary Lynn Rae, RN, MSN, CPHON

    Clinical Educator Hem/Onc/SCT & VAT

    Ann & Robert H. Lurie Children’s Hospital of Chicago

    T 312.227.4224 | |

    225 East Chicago Avenue, Box 248, Chicago, Illinois 60611-2991

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    ——Original Message——

    Hoping for any experience you all have to share with regard to CAR-T referrals from other institutions. My questions are as follows:

    1. When you receive a referral for CAR-T therapy, who manages the chemotherapy and labs prior to collection? Do you always allow the referring institution to manage that chemo, knowing that as the patient is recovering, you have to get them in the small window they may have between ALC recovery and blasting off?
      1. If you do allow them to manage, at what point do you take over lab monitoring, so you are sure to hit the collection window?
    2. For bridging chemotherapy, while cells are being manufactured, do you always allow the referring institution to manage that treatment, with input from your team?
    3. Any other details you have to share would be much appreciated!


    Michelle Gillard, MSN, RN, CPHON
    Cellular Therapy Program Coordinator
    Phoenix Children’s Hospital
    Phoenix, AZ