Reply To: care patients receiving thiotepa

  • Caroline Costello

    Member
    June 24, 2021 at 7:41 am

    Hello,
    My answers are below in red. If you would like I can send the reference tool.
    1. frequent bath for 24 hours or 48 hours after thiotepa? During Thiotepa baths are every 6 hours up to 24 hours after the last dose.
    2. can use soap or just advise using warm water only ? Water only, no soaps, creams, or lotions. Also, no CHG baths until Day +21. They shower, we don’t rub the skin during the bath.
    3. frequency of changing central line dressing during receiving thiotepa? can still use transparent dressing like opsite dressing for covering the wound ? or only gauze is recommended?  No tape or occlusive dressings, clean with sterile water and use small 2×2 gauze with a mesh over it to keep secure. 

    Sometimes ever with all of this we still have patients who have burns.

    Let me know if there is anything else I can help you with.

    Caroline

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    Caroline Costello RN, MBA, CPON, BMTCN
    Nursing Clinical Education Coordinator
    Boston Children’s Hospital
    caroline.costello@childrens.harvard.edu
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    Original Message:
    Sent: 06-23-2021 11:23 PM
    From: Wingsze Kong
    Subject: care patients receiving thiotepa

    hi all,

    We currently experienced a HSCT patient with severe skin burn reaction after 20 days of stem cell infusion. The doctors questioned the cause of the skin condition might caused by the thiotepa which gave in the conditioning protocol. Our institution only advice patients bath 2/ day for 24 hours after thiotepa, but do not have any guidelines or worksheet to follow. Therefore, I would like to ask is anyone willing to share their hospitals standards for caring patients receiving thiotepa? also I have some questions about caring patients receiving thiotepa:
    1. frequent bath for 24 hours or 48 hours after thiotepa?
    2. can use soap or just advise using warm water only ?
    3. frequency of changing central line dressing during receiving thiotepa? can still use transparent dressing like opsite dressing for covering the wound ? or only gauze is recommended?

    Thank you very much.

    Wing sze Kong
    Hong Kong Children’s Hospital