Reply To: care patients receiving thiotepa

  • Apryl Norris

    June 25, 2021 at 8:50 am

    Our policy is a bath q6 hours, change the dressing to a primapore and clean and change after every bath. We change the dressing to the primapore when we start the infusion, and begin baths roughly 6 hours later (we try to do a 4,10 or 6,12 schedule for convenience). We continue these throughout the infusion and 24 hours after. If the dressing area becomes irritated from the cleaning, we use sterile gauze over site with an ace wrap around chest that we change every bath. Also loose diapers and clothing, in diaper or underwear if small. We also use the alcohol/beta done instead of the chloroprep during this. Hope this helps.

    Apryl Norris, RN, BSN
    Charge Nurse, ūüéóHeme/Onc/BMTūüéó
    (205) 265-9584

    Original Message:
    Sent: 6/24/2021 12:23:00 AM
    From: Wingsze Kong
    Subject: care patients receiving thiotepa

    hi all, 

    We currently experienced a HSCT patient with severe skin burn reaction after 20 days of stem cell infusion. The doctors questioned the cause of the skin condition might caused by the thiotepa which gave in the conditioning protocol. Our institution only advice patients bath 2/ day for 24 hours after thiotepa, but do not have any guidelines or worksheet to follow. Therefore, I would like to ask is anyone willing to share their hospitals standards for caring patients receiving thiotepa? also I have some questions about caring patients receiving thiotepa: 
    1. frequent bath for 24 hours or 48 hours after thiotepa? 
    2. can use soap or just advise using warm water only ?
    3. frequency of changing central line dressing during receiving thiotepa? can still use transparent dressing like opsite dressing for covering the wound ? or only gauze is recommended? 

    Thank you very much. 

    Wing sze Kong 
    Hong Kong Children’s Hospital¬†