Reply To: Replenishing Magnesium when on Cyclosporine or Tacrolimus

  • Nicola Jones

    September 10, 2021 at 8:23 am

    Good morning,

    We replete Magnesium for levels <1.6 in transplant, this is for both allo/auto, regardless of other medications. Hope that helps!


    Nicola Jones, APRN, FNP-C, CPHON, AOCNP, BMTCN

    Division of Pediatric Hematology/Oncology/Blood and Marrow Transplant and Cellular Therapy

    Norton Children’s Hospital

    231 East Chestnut Street, 7 West

    Louisville, KY 40202

    (502) 744-4833 (C)

    (502) 629-8817 (P)

    (502) 629-4635 (F)


    Original Message:
    Sent: 09-09-2021 04:50 PM
    From: Caroline Costello
    Subject: Replenishing Magnesium when on Cyclosporine or Tacrolimus

    I am doing an EBP project regarding magnesium replacement for patients on Cyclosporine and Tacrolimus and there is not much in the literature. My question is:

    Do patients who received an allogeneic HSCT who are now on Tacrolimus or Cyclosporine get replenished for low magnesium levels? If so what is the threshold in which they are replenished?<o:p>

    Thank you,


    Caroline Costello RN, MBA, CPON, BMTCN
    Nursing Education Coordinator
    Boston Children’s Hospital