Reply To: TPA administration by nurse or physician

  • Erica Fernandez

    November 17, 2019 at 8:32 pm

    At our Hospital the Central line nurse administers and aspirate the TPA. But if there is not a CLRN then we call our Vascular Access Team they handle all the central line needs of the hospital, except for those few units that have CLRN’s. But no one else can administer TPA.

    Erica Fernandez, RN
    Pasadena, TX
    United States
    Original Message:
    Sent: 11-17-2019 08:21 PM
    From: Marva Grootfaam-Phillips
    Subject: TPA administration by nurse or physician

    Hi Sarah,

    At or facility, it is the nurse that administers and aspirate the TPA. A second RN is in the room to verify medication at the bedside.
    The priming volume of the port is 0.5-1 ml, but consider that the line beyond the dome maybe where the clot is.
    Hope this helps,

    Original Message——


    it is highly appreciated if you can help with below inquiries:

    1- who administer TPA in case of an occluded line : the doctor or a the nurse?
     In our setting, the MD administers the TPA dose and the nurse aspirate it.

    please advise if the nurse administers the dose.

    2- what is the priming volume of an implanted port chamber.
    does the priming volume affects the amount of thrombolytic agent (TPA)  to be given in case of an occluded line?

    Thank you in advance

    Sarah Hakim, MSN,RN
    Clinical Educator