Reply To: TPA administration by nurse or physician

  • Angie Blackwell

    November 18, 2019 at 12:06 pm

    At our facility the RN administers the tPA. We have recently changed our policy so that our dosing is 110% of internal priming volume for all lines.


    Angie Blackwell, MSN, RN, CNS, CPON

    Clinical Nurse Specialist – Hematology/Oncology

    CHOC Children’s Hospital

    1201 West La Veta Avenue

    Orange, CA 92868

    (714) 509-4089 Phone 58754 Ascom

    A Clinical Nurse Specialist is a master’s prepared nurse who implements evidence-based practice to improve patient outcomes, advance nursing practice, and influence system changes within the organization.

    CHOC Children’s Hospital…The future is bright!


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    ——Original Message——

    Hi Sarah,

    At or facility, it is the nurse that administers and aspirate the TPA. A second RN is in the room to verify medication at the bedside.
    The priming volume of the port is 0.5-1 ml, but consider that the line beyond the dome maybe where the clot is.
    Hope this helps,