Reply To: cetirizine for premed?

  • Kathleen Ackerman

    January 19, 2023 at 3:35 pm
    we use loratadine and cetirizine for premeds for chemo, interested in using for blood, however, we recently stopped using a lot of premeds for blood unless there was a witnessed/reasonable belief of a previous reaction. 

    Kathleen (Kathy) Ackerman, MSN, RN, PCNS-BC
    Clinical Nurse Specialist, Pediatrics

    Department of Evidence Based Practice

    MSK Kids
    Memorial Sloan Kettering Cancer Center

    1275 York Avenue, M-9
    New York, NY 10065
    T 212-639-6911 pager 917-205-9200 x 7845

    A clinical nurse specialist is an advanced degree nurse who influences practices and patient outcomes through consultation, research, education and establishing organizational standards.


    Original Message:
    Sent: 1/19/2023 3:28:00 PM
    From: Marge Ancliffe
    Subject: RE: cetirizine for premed?

    We routinely use Cetirizine for pre-medication for blood/blood products and chemotherapy.  We dose at 0.25mg/kg to a max of 10mg per dose.  Our hospital has significantly lessened the use of IV Diphenhydramine due to the unpredictable side effect profile – although we can still access it on our formulary.  Since we implemented Cetirizine pre-meds, I can count on one hand how many times I’ve needed to order Diphenhydramine!

    Marge Ancliffe, NP
    Pediatric Oncology NP
    IWK Health
    Halifax, NS
    Original Message:
    Sent: 01-19-2023 02:18 PM
    From: Monica Ploof
    Subject: cetirizine for premed?

    I have successfully used cetirizine in patients who had previous reactions while receiving blood products, IVIG, and chemotherapy. These patients were able to tolerate infusion successfully with cetirizine as pre-med. Reasons for not using Benadryl were due to excessive aggressive behavior, tearful, extreme pruritis or generalized intolerance of the drug.


    Monica M. Ploof CPNP

    Pediatric Hematology/Oncology

    University of Vermont Medical Center


    Original Message:
    Sent: 1/19/2023 2:29:00 PM
    From: Jami Gattuso
    Subject: cetirizine for premed?

    Does anyone use cetirizine as a pre-med for chemo or blood products?  Thanks, Jami

    Jami Gattuso, CPON,MSN,RN
    Nursing Research Specialist
    Memphis, TN
    United States