Reply To: Consents and Vincristine Laden Platelets

  • Colleen Nixon

    August 23, 2015 at 6:29 pm

    I have never heard of this, so the issue has not been addressed @ Boston Children’s Hospital or the Jimmy Fund Clinic (DFCI).

    Colleen Nixon, CPON,MSN
    Children’s Hospital Boston
    Boston, MA
    United States

    Original Message:
    Sent: 08-22-2015 02:18 PM
    From: Maritza Salazar Abshire
    Subject: Consents and Vincristine Laden Platelets

    hello all!

    We recently had a physician write for vincristine laden platelets for a patient who is refractory to platelet transfusions. Our Chemo policy does not address this blood product specifically as a circumstance where a chemo consent is needed, the blood product consent does not address this either. As the vincristine in these platelets may cause or intensify neuropathies related to vinca alkaloids (we have seen this happen in our adult population) does your institution require a chemo consent for vincristine laden platelets? Any thoughts, replies or help would be appreciated as I am trying to benchmark prior to bringing the issue to our institutional medication safety committee. 

    Thanks so much!!


    [Maritza] [Salazar-Abshire], [MSN, MED, RN, CPON]
    [Senior Nursing Instructor]
    [The Children’s Cancer Hospital at The University of Texas MD Anderson Cancer Center]
    [Houston], [Texas]