This specialty practice discussion group is intended for nurse educator members of APHON. Remember that... View more
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I posed this question to one of my attending physicians and here was her response:
If the CARs are persisting and the patient has B cell aplasia, then vaccines will not be efficacious. Once you have documented good immune reconstitution in terms of B cell numbers and the patient is no longer IVIG-dependent, then we can re-immunize.
—————————— Letty Valdiviez, MSN, RN, CPHON CAR T Coordinator Children’s Hospital Los Angeles —————————— ——————————————- Original Message: Sent: 08-08-2018 02:09 PM From: Michelle Gillard Subject: Vaccines S/P CAR-T
Hello from Phoenix, Since many of you are now doing CAR-T at your institutions, I’m wondering if you have an SOP or plan for vaccines s/p CAR-T infusion? Are you using the 6 months s/p treatment end (and is that day of infusion) for live vaccines or a more conservative approach as these kids are usually managed by the BMT team? If you can, please share:
Timeline to live vaccines:
Timeline to inactive/attenuated vaccines
Thank you for sharing! Michelle
—————————— Michelle Gillard, MSN, RN, CPHON Cellular Therapy Program Coordinator Phoenix Children’s Hospital Phoenix, AZ email@example.com ——————————