Reply To: Vaccines S/P CAR-T

  • Michelle Gillard

    August 10, 2018 at 11:35 am

    Thank you! That makes absolute sense J


    ——Original Message——

    I posed this question to one of my attending physicians and here was her response: 

    If the CARs are persisting and the patient has B cell aplasia, then vaccines will not be efficacious. Once you have documented good immune reconstitution in terms of B cell numbers and the patient is no longer IVIG-dependent, then we can re-immunize.

    Letty Valdiviez, MSN, RN, CPHON
    CAR T Coordinator
    Children’s Hospital Los Angeles