Reply To: TPA administration by nurse or physician

  • Sarah Walding

    December 13, 2019 at 10:44 am

    Good Morning–

    The RN administers and aspirates Alteplase for an occluded line. 

    We administer 2ml of Cath-flo.
    Under 10 kg is 0.5mg/2ml
    10kg and above is  2kg/2ml

    Sarah Walding, BSN, RN, CPN
    Clinical Practice Specialist
    Pediatric Hematology/Oncology
    Advocate Children’s Hospital Park Ridge
    Original Message:
    Sent: 10-31-2019 01:46 AM
    From: Sarah Hakim
    Subject: TPA administration by nurse or physician


    it is highly appreciated if you can help with below inquiries:

    1- who administer TPA in case of an occluded line : the doctor or a the nurse?
     In our setting, the MD administers the TPA dose and the nurse aspirate it.

    please advise if the nurse administers the dose.

    2- what is the priming volume of an implanted port chamber.
    does the priming volume affects the amount of thrombolytic agent (TPA)  to be given in case of an occluded line?

    Thank you in advance

    Sarah Hakim, MSN,RN
    Clinical Educator