Reply To: observation time s/p asparaginase

  • Kimberly Duback

    January 2, 2018 at 2:01 pm

    ​At my institution, we continue to monitor patients 1 hour post administration, regardless of route.  We base this practice off of the package insert for the drug, which specifies 1 hour monitoring and does not site a specific route for this recommendation.

    Kimberly Duback, MS, APN, PCNS-BC, CPN, CPHON
    Advanced Practice Nurse
    Advocate Children’s Hospital
    Oak Lawn, IL
    United States of America
    Original Message:
    Sent: 01-02-2018 01:34 PM
    From: Kathleen Morris
    Subject: observation time s/p asparaginase

    Our standard has always been to observe our patients for one hour after administration of asparaginase.  Recently a NP discussed this practice with a pharmacist who felt that this was not necessary with IV dosing (but should continue with IM dosing due to slow absorption time).  I have seen some significant reactions to asparaginase.

    What is the practice at your institution?

    Kathleen Morris, MSN, RN
    Assistant Nurse Manager
    Rochester, NY
    United States