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Evidence Based Practice

Evidence-Based Practice Guidelines

APHON’s Evidence-Based Practice and Research Committee supports the development of Evidence-Based Practice Guidelines and supports research activities within the membership optimizing outcomes for children, adolescents, and young adults with cancer and blood disorders.

Method of Review

A subcommittee of the Evidence-Based Practice and Research Committee of the Association of Pediatric Hematology/Oncology Nurses conducted a group review of clinical recommendations using the AGREE II Instrument. The committee requires an overall assessment of approval for listing on this website.

Clinical Guidelines

All Guidelines are listed in alphabetical order by subject matter. There is no implied priority in the listing of the guidelines.

Side Effects

  • Anorexia

    DATE OF PUBLICATION:
    FEBRUARY 2017
    DATE OF REVIEW:
    FALL 2018
    Anorexia (ONS PEP Topic)

  • Cytokine Release Syndrome

    DATE OF PUBLICATION:
    NOVEMBER/DECEMBER 2021
    DATE OF REVIEW:
    DECEMBER 1, 2021
    Evidence-Based Recommendations for Nurse Monitoring and Management of Immunotherapy-Induced Cytokine Release Syndrome: A Systematic Review from the Children’s Oncology Group

  • EPB Guideline Asparaginase Nurse Monitoring

    DATE OF PUBLICATION:
    2017
    DATE OF REVIEW:
    JANUARY 2019
    Evidence-Based Practice Recommendations for Peg-Asparaginase Nurse Monitoring, Hypersensitivity Reaction Management, and Patient/Family Education from the Children’s Oncology Group

  • EPB Guideline Chemo Induced Nausea Prevention

    DATE OF PUBLICATION:
    APRIL 23, 2014
    DATE OF REVIEW:
    JUNE 2014
    Guideline for the Prevention and Treatment of Anticipatory Nausea and Vomiting due to Chemotherapy in Pediatric Cancer Patients

  • EPB Guideline Chemo Vomiting

    DATE OF PUBLICATION:
    APRIL 2017
    DATE OF REVIEW:
    JANUARY 2018
    Chemotherapy-Induced Nausea and Vomiting-Pediatric (ONS Pep Topic)

  • EPB Guideline Constipation

    DATE OF PUBLICATION:
    FEBRUARY 2017
    DATE OF REVIEW:
    FALL 2018
    Constipation (ONS PEP Topic)

  • EPB Guideline Fever And Nuropenia In HSCT

    DATE OF PUBLICATION:
    2017
    DATE OF REVIEW:
    OCTOBER 2019
    Guidelines for the Management of Fever and Neutropenia in Children with Cancer and Hematopoietic Stem Cell Transplantation Recipients: 2017 Update

  • EPB Guideline Infection

    DATE OF PUBLICATION:
    APRIL 2017
    DATE OF REVIEW:
    JANUARY 2018
    Prevention of Infection (ONS PEP Topic)

  • EPB Guideline Mucositis

    DATE OF PUBLICATION:
    MAY 2017
    DATE OF REVIEW:
    JANUARY 2018
    Mucositis (ONS PEP Topic)

  • EPB Guideline Nausea

    DATE OF PUBLICATION:
    APRIL 23, 2014
    DATE OF REVIEW:
    JUNE 2014
    Guideline for the Prevention and Treatment of Anticipatory Nausea and Vomiting due to Chemotherapy in Pediatric Cancer Patients

  • EPB Guideline Sedation To Manage Pain

    DATE OF PUBLICATION:
    2019
    DATE OF REVIEW:
    JUNE 8, 2020
    Evidence-Based Recommendations for the Appropriate Level of Sedation to Manage Pain in Pediatric Oncology Patients Requiring Procedures: A Systematic Review From the Children’s Oncology Group

  • Fertility Preservation Options

    DATE OF PUBLICATION:
    2014
    DATE OF REVIEW:
    APRIL 2, 2018
    Evidence-Based Practice Recommendations to Fertility Preservation Options for Inclusion in Treatment Protocols for Pediatric and Adolescent Patients Diagnosed with Cancer

  • Peripheral Neuropathy

    DATE OF PUBLICATION:
    2018
    DATE OF REVIEW:
    JULY 30, 2018
    Assessment Tools for Peripheral Neuropathy in Pediatric Oncology: A Systematic Review from the Children’s Oncology Group

  • Post Lumbar Pucture Headaches

    DATE OF PUBLICATION:
    2014
    DATE OF REVIEW:
    MAY 10, 2018
    Evidence-Based Practice Recommendations to Prevent/Manage Post Lumbar Puncture Headaches in Pediatric Patients Receiving Intrathecal Chemotherapy

Patient Care Management

Other Endorsed Guidelines

The APHON EBP/Research Committee is proud to list the COG Endorsed Supportive Care Guidelines as a resource for pediatric oncology nurses. A multi-disciplinary group of the Supportive Care Committee within COG has very stringently reviewed these guidelines and endorsed them.

Resources for developing an Evidenced Based Practice Project

Duke University EBP tutorial

Research Tools

The Cochrane Database | US National Library/ National Institutes of Health | Turning Research into Practice

Additional Resource

Bibliography | ECRI Guideline Trust

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